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Funding This study was supported by grants from the National Science and Technology Council (NSTC 1122740-B-002002, MOST 1112740-B-002004, NSTC 1122314-B-002140, NSTC 1132314-B-002240)

This metabolite enhances hepatic de novo lipogenesis by activating ChREBP and SREBP-1 pathways and induces mitochondrial dysfunction, thereby promoting hepatic steatosis

At The Spa MD, patient education is a priority

Conflict of interest Authors A.C., A.P., F.B

Slides were mounted with Fluoromount-G (Southern Biotech, USA) and examined using a Leica TCS SP5 AOBS confocal laser scanning microscope (Leica Microsystems, Germany) equipped with HCX PL APO 63 oil (NA = 1.4) objectives

Liu Y, Wu W